Hydrochloric Acid → HCID 67248361, compound

HRID 2175125Notes

Reaction equation

HRID 2175125 reaction equation
[CH3:1][C:2]1([CH3:27])[CH2:11][CH2:10][C:9]([CH3:13])([CH3:12])[C:8]2[CH:7]=[C:6]([C:14]3[N:19]=[C:18]([N:20]4[CH2:26][CH2:25][CH2:24][NH:23][CH2:22][CH2:21]4)[CH:17]=[CH:16][CH:15]=3)[CH:5]=[CH:4][C:3]1=2.Cl[CH2:29][CH2:30][CH2:31][OH:32].Cl>>[CH3:1][C:2]1([CH3:27])[CH2:11][CH2:10][C:9]([CH3:12])([CH3:13])[C:8]2[CH:7]=[C:6]([C:14]3[N:19]=[C:18]([N:20]4[CH2:26][CH2:25][CH2:24][N:23]([CH2:29][CH2:30][CH2:31][OH:32])[CH2:22][CH2:21]4)[CH:17]=[CH:16][CH:15]=3)[CH:5]=[CH:4][C:3]1=2

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 123133-Chloro-1-propanolHCID 67247818HCID 67247818, compound

Product 1

HCID 67248361HCID 67248361, compound

Procedure

The preparation is carried out analogously to FS301 starting from 66 mg (0.18 mmol) of 1-[6-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)-pyridin-2-yl]-1,4-diazepane and 18 μl of 3-chloro-1-propanol. The product is the hydrochloride.

Sources & evidence

ORD record
ord-3b1d22b27d7245c79cb9d2373134fd69
Source dataset
uspto-grants-2015_06
Patent number
US09062015B2

Reaction notes

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