Hydrochloric Acid → HCID 86731174, compound

Participants

Reaction Steps

10% hydrogen chloride in methanol (3 mL) was added to a solution of 2-[4-(tert-butoxycarbonyl)homopiperazine-1-carbonyl]pyrrolo[1,2-a]quinazolin-5(4H)-one (the above Compound 1-47, 156 mg, 0.380 mmol) in methanol (1 mL), and the reaction solution was stirred overnight at room temperature. The precipitated solid was collected by filtration, and dried under reduced pressure, to obtain the title compound (102 mg, yield: 87%) as a colorless powder.

Provenance & Evidence