HuagongsheHuagongshe Chemistry Print Report · For research reference only
Lithium Hydroxide → HCID 62341954, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Lithium Hydroxide | HCID 3939 | — |
| Reactant | HCID 86719392 | HCID 86719392 | — |
| Solvent | Water | HCID 962 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 62341954 | HCID 62341954 | — |
Reaction Steps
(E)-Methyl 4-(bis(2-methoxyethyl)amino)but-2-enoate (77) (10.0 g, 43 mmol) was hydrolyzed with LiOH (5.4 g, 130 mmol) in THF (100 mL) and H2O (50 mL) to give (E)-4-(bis(2-methoxyethyl)amino)but-2-enoic acid (78) (quantative yield) as a yellow oil. LC-MS (ESI): m/z (M+1) 218.1.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09062058B2 |
| Source dataset | uspto-grants-2015_06 |
| ORD ID | ord-41db504dd94541da84097f0d07b6942c |
| Source note | uspto-grants-2015_06 |