反应详情

温度

120 °C

As shown in the Reaction Scheme 8, a mixture of 3-chloropropyldimethylvinylsilane (1.0 g, 6.15 mmol) and sodium acetate (1.01 g, 12.3 mmol) was dissolved in 17 mL of N,N′-dimethylformamide (DMF), and the resulting solution was heated at 120° C. for 12 hours. After the reaction, the organic layer was extracted with distilled water and ether. After evaporating the solvent, the resulting residue was purified by column chromatography (n-Hex:EA=10:1, Rf=0.36) to give 859 mg (75% yield) of pure 3-acetoxypropyldimethylvinylsilane.

1. customAs shown in the Reaction Scheme 8
2. customAfter the reaction
3. extractionthe organic layer was extracted with distilled water and ether
4. customAfter evaporating the solvent
5. customthe resulting residue was purified by column chromatography (n-Hex:EA=10:1, Rf=0.36)