反应详情

温度

120 °C

As shown in Reaction Scheme 24, 3-chloropropyltrivinylsilane (1.0 g, 5.35 mmol) and sodium acetate (0.87 g, 10.7 mmol) were dissolved in 17 mL of dimethylformamide (DMF), and the reaction mixture was heated at 120° C. for 12 hours. After the reaction, the organic layer was separated after addition of distilled water and ether. The organic layer was dried over MgSO4, concentrated by evaporation of solvent, and the resulting residue was purified by column chromatography (n-Hex: EA=10:1, Rf=0.4) to give 855 mg (76% yield) of pure 3-acetoxypropyltrivinylsilane.

1. customAfter the reaction
2. customthe organic layer was separated
3. additionafter addition of distilled water and ether
4. dry with materialThe organic layer was dried over MgSO4
5. concentrationconcentrated by evaporation of solvent
6. customthe resulting residue was purified by column chromatography (n-Hex: EA=10:1, Rf=0.4)