反应详情

温度

70 °C

Compound 3-chloropropyltrivinylsilane (1000 mg, 5.35 mmol) and sodium cyanide (525 mg, 10.70 mmol) were dissolved in 18 ml of dimethylformamide, and the mixture was heated at 70° C. for 4 hours. After the reaction, the organic layer was extracted after addition of distilled water and ether, and then purified by column chromatography (n-Hex:EA=10:1, Rf=0.42), to give 818 mg (86% yield) of pure 3-cyanopropyltrivinylsilane.

1. customAfter the reaction
2. extractionthe organic layer was extracted
3. additionafter addition of distilled water and ether
4. custompurified by column chromatography (n-Hex:EA=10:1, Rf=0.42)