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HRID2175830

反应详情

EQUATION

反应方程式

HRID 2175830 的结构方程式

REACTANTS

反应物

3
结构：CC(C)(C)OC(=O)N1CCN[C@@H](CO)C1
HCID24820286

tert-Butyl (3R)-3-(hydroxymethyl)piperazine-1-carboxylate

C10H20N2O3

结构：Cc1c(C2CO2)ccc(F)c1C#N
HCID86647307

未命名化合物

结构：Cc1c([C@@H]2CN3CCNC[C@H]3CN2C(=O)OC(C)(C)C)ccc(F)c1C#N
HCID86727053

未命名化合物

PRODUCTS

生成物

1
结构：Cc1c([C@H]2CN3CCNC[C@@H]3CN2C(=O)OC(C)(C)C)ccc(F)c1C#N
HCID86727055

未命名化合物

PROCEDURE

实验过程

The title compound was prepared in an analogous fashion to that described for the synthesis of (3R,9aS)-tert-butyl 3-(3-cyano-4-fluoro-2-methylphenyl)hexahydro-1H-pyrazino[1,2-a]pyrazine-2(6H)-carboxylate starting from 6-fluoro-2-methyl-3-(oxiran-2-yl)benzonitrile and (R)-tert-butyl 3-(hydroxymethyl)piperazine-1-carboxylate. LC/MS: 375.16 (M+1)+.