HCID 86693023, compound → HCID 67516507, compound

HRID 2175913Notes

Reaction equation

HRID 2175913 reaction equation
CC(C)(C)C([NH:5][C:6]1[N:11]=[CH:10][C:9]2[CH:12]([C:15]([O-:17])=[O:16])[CH2:13][CH2:14][C:8]=2[CH:7]=1)=O>Cl>[NH2:5][C:6]1[N:11]=[CH:10][C:9]2[CH:12]([C:15]([OH:17])=[O:16])[CH2:13][CH2:14][C:8]=2[CH:7]=1

Participants

3

Reactant 1

HCID 86693023HCID 86693023, compound

Product 1

HCID 67516507HCID 67516507, compound

Reagents, catalysts & solvents 1

HCID 313Hydrochloric AcidSolvent

Procedure

A solution of 3-[(2,2-dimethylpropanoyl)amino]-6,7-dihydro-5H-cyclopenta[c]pyridine-7-carboxylate (0.624 mg, 1.96 mmol) in 6N hydrochloric acid (25 mL) was heated to reflux for 24 h. The solution was cooled and concentrated to provide the title compound which was used without further purification in the next step: LC/MS (M+1)+=179.0.

Workup

  1. temperatureto reflux for 24 h
  2. temperatureThe solution was cooled
  3. concentrationconcentrated

Sources & evidence

ORD record
ord-fd6fb648aec444d5a76d36c6c414c098
Source dataset
uspto-grants-2015_06
Patent number
US09062070B2

Reaction notes

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