Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | HCID 90412916 | HCID 90412916 | — |
| Solvent | Isopropanol | HCID 3776 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | HCID 90411982 | HCID 90411982 | — |
Reaction Steps
To the title compound from step A (474 mg, 1.5 mmol) in 1,4-dioxane (1.5 mL) was added 6N HCl in iPrOH (1.5 mL). The reaction was heated to 40° C. for 1.5 h and concentrated to give the title compound that was used without further purification in subsequent steps. MS (ESI) mass calcd. for C11H14FN3O, 223.1; m/z found 224.0 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US09062078B2 |
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| Source dataset | uspto-grants-2015_06 |
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| ORD ID | ord-45e6c8c823da4ba0873d26483468d182 |
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| Source note | uspto-grants-2015_06 |
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