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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2175969Generated: October 31, 2026

Hydrochloric Acid → HCID 90411982, compound

https://huagongshe.com/reaction/2175969

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantHCID 90412916HCID 90412916—
SolventIsopropanolHCID 3776—
Solvent1,4-DioxaneHCID 31275—
ProductHCID 90411982HCID 90411982—

Reaction Conditions

Temperature40 °C

Reaction Steps

To the title compound from step A (474 mg, 1.5 mmol) in 1,4-dioxane (1.5 mL) was added 6N HCl in iPrOH (1.5 mL). The reaction was heated to 40° C. for 1.5 h and concentrated to give the title compound that was used without further purification in subsequent steps. MS (ESI) mass calcd. for C11H14FN3O, 223.1; m/z found 224.0 [M+H]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09062078B2
Source datasetuspto-grants-2015_06
ORD IDord-45e6c8c823da4ba0873d26483468d182
Source noteuspto-grants-2015_06