Trifluoroacetic acid → HCID 90411797, compound

HRID 2175973Notes

Reaction equation

HRID 2175973 reaction equation
[N:1]([CH2:4][CH:5]1[CH2:10][CH:9]2[N:11](C(OC(C)(C)C)=O)[CH:6]1[CH2:7][CH2:8]2)=[N+:2]=[N-:3].C(O)(C(F)(F)F)=O>C(Cl)Cl>[N:1]([CH2:4][CH:5]1[CH2:10][CH:9]2[NH:11][CH:6]1[CH2:7][CH2:8]2)=[N+:2]=[N-:3]

Participants

4

Reactant 2

HCID 6422Trifluoroacetic acidHCID 90411574HCID 90411574, compound

Product 1

HCID 90411797HCID 90411797, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

To the title compound of step B in DCM was added TFA. After 3 h at rt, the reaction mixture was concentrated to give the title compound (1.7 g) as the TFA salt.

Workup

  1. concentrationthe reaction mixture was concentrated

Sources & evidence

ORD record
ord-3f4e9cfc3e2f4f00b420d3cfb949ba0b
Source dataset
uspto-grants-2015_06
Patent number
US09062078B2

Reaction notes

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