HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → HCID 90370050, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | Carbamic acid, [2-(cyclopropylamino)ethyl]-, 1,1-dimethylethyl ester (9CI) | HCID 45091939 | — |
| Reactant | HCID 90370193 | HCID 90370193 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 90370050 | HCID 90370050 | 97.7% |
Reaction Steps
By using 2.0 g of methyl 4-[2-(4-{[(2-{[3-(chloromethyl)benzoyl]amino}-4,5,6,7-tetrahydro-1-benzothiophen-3-yl)carbonyl]amino}phenyl)ethyl]benzoate, 1.0 g of tert-butyl[2-(cyclopropylamino)ethyl]carbamate, 0.76 g of potassium carbonate, and 40 mL of DMF, 2.5 g of methyl 4-(2-{4-[({2-[(3-{[{2-[(tert-butoxycarbonyl)amino]ethyl}(cyclopropyl)amino]methyl}benzoyl)amino]-4,5,6,7-tetrahydro-1-benzothiophen-3-yl}carbonyl)amino]phenyl}ethyl)benzoate was obtained by the method similar to Preparation Example 9.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09062032B2 |
| Source dataset | uspto-grants-2015_06 |
| ORD ID | ord-b2904962d1a048679ab0dfb83fba3272 |
| Source note | uspto-grants-2015_06 |