Hydrogen chloride-ethyl acetate → HCID 90370286, compound

Participants

Reaction Steps

To 4.8 g of tert-butyl ethyl 2,2′-piperazine-1,4-diyldiacetate was added 20 mL of a 4M hydrogen chloride/ethyl acetate solution, followed by stirring for 2 hours at room temperature. The generated insoluble material was collected by filtration, thereby obtaining 4.0 g of [4-(2-ethoxy-2-oxoethyl)piperazin-1-yl]acetic acid dihydrochloride.

Provenance & Evidence