Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | HCID 68802969 | HCID 68802969 | — |
| Product | HCID 90370160 | HCID 90370160 | — |
Reaction Steps
A mixture of 3.01 g of methyl 5-(morpholin-4-ylmethyl)thiophene-2-carboxylate and 30 mL of 6.0 M hydrochloric acid was subjected to heating under reflux overnight at 100° C. The reaction mixture was concentrated under reduced pressure, and the residue was washed with acetonitrile, thereby obtaining 3.05 g of 5-(morpholin-4-ylmethyl)thiophene-2-carboxylic acid hydrochloride.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US09062032B2 |
|---|
| Source dataset | uspto-grants-2015_06 |
|---|
| ORD ID | ord-ae05f8f1a2144a68a9954a6788c5b044 |
|---|
| Source note | uspto-grants-2015_06 |
|---|
