1-Acetyl-N-cyclopropylpiperidin-4-amine → HCID 90370134, compound

Participants

Reaction Steps

By using 5.34 g of 2-{[3-(chloromethyl)benzoyl]amino}-N-[4-(diethylamino)phenyl]-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide and 13.1 g of 1-[4-(cyclopropylamino)piperidin-1-yl]ethanone as starting materials, a reaction was performed under the conditions similar to Preparation Example 29, thereby obtaining 5.37 g of 2-[(3-{[(1-acetylpiperidin-4-yl)(cyclopropyl)amino]methyl}benzoyl)amino]-N-[4-(diethylamino)phenyl]-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide.

Provenance & Evidence