反应详情

6-Chloro-[1,2,4]triazolo[4,3-b]pyridazin-3-ylamine hydrobromide (W2.001; 1.1 g) was taken up with a large amount of water and alkalized with saturated potassium carbonate solution. The solid which precipitated out was filtered off with suction and dried (388 mg). Repeated extraction of the mother liquor with dichloromethane, drying of the combined organic phases over sodium sulfate, filtration and concentration afforded a further 228 mg of product in total.

1. customThe solid which precipitated out
2. filtrationwas filtered off with suction
3. customdried (388 mg)
4. extractionextraction of the mother liquor with dichloromethane
5. dry with materialdrying of the combined organic phases over sodium sulfate, filtration and concentration