HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → 4-Chlorobenzenepropanoyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | beta-(p-Chlorophenyl)propionic acid | HCID 123137 | — |
| Product | 4-Chlorobenzenepropanoyl chloride | HCID 12206516 | — |
Reaction Steps
3-(4-Chlorophenyl)-propionic acid (3.83 g; 20.7 mmol) is dissolved in 50 ml thionyl chloride and stirred at room temperature overnight. The excess thionyl chloride is removed by rotary evaporation to give 3-(4-chlorophenyl)-propionyl chloride as a pale yellow oil, which is used without purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09067897B2 |
| Source dataset | uspto-grants-2015_06 |
| ORD ID | ord-2326e59681084aad94115a1e1a747815 |
| Source note | uspto-grants-2015_06 |