Iodoethane → 2-Ethyl-4,6-bis-trifluoromethyl-benzoic acid

HRID 2177511Notes

Reaction equation

HRID 2177511 reaction equation
[F:1][C:2]([F:17])([F:16])[C:3]1[CH:11]=[C:10]([C:12]([F:15])([F:14])[F:13])[CH:9]=[CH:8][C:4]=1[C:5]([OH:7])=[O:6].[CH2:18](I)[CH3:19]>>[CH2:18]([C:8]1[CH:9]=[C:10]([C:12]([F:15])([F:13])[F:14])[CH:11]=[C:3]([C:2]([F:16])([F:17])[F:1])[C:4]=1[C:5]([OH:7])=[O:6])[CH3:19]

Participants

3

Reactant 2

HCID 6340IodoethaneHCID 1417522,4-Bis(trifluoromethyl)benzoic acid

Product 1

HCID 591979342-Ethyl-4,6-bis-trifluoromethyl-benzoic acid

Procedure

In analogy to the procedure described for the synthesis of example B.1, the title compound was prepared from 2,4-bis-trifluoromethyl-benzoic acid (commercial) and ethyliodide.

Sources & evidence

ORD record
ord-58a7eadd8a944d659164c0a6993925f9
Source dataset
uspto-grants-2015_06
Patent number
US09067911B2

Reaction notes

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