Iodoethane → Methyl 3-tert-butyl-5-ethoxymethylbenzoate

HRID 217752Notes

Reaction equation

[C:1]([C:5]1[CH:6]=[C:7]([CH:12]=[C:13]([CH2:15][OH:16])[CH:14]=1)[C:8]([O:10][CH3:11])=[O:9])([CH3:4])([CH3:3])[CH3:2].[CH2:17](I)[CH3:18]>>[C:1]([C:5]1[CH:6]=[C:7]([CH:12]=[C:13]([CH2:15][O:16][CH2:17][CH3:18])[CH:14]=1)[C:8]([O:10][CH3:11])=[O:9])([CH3:4])([CH3:2])[CH3:3]

Participants

Reactant 2

HCID 6340Iodoethane

HCID 12144659Methyl 3-tert-butyl-5-(hydroxymethyl)benzoate

Product 1

HCID 58136853Methyl 3-tert-butyl-5-ethoxymethylbenzoate

Procedure

Methyl 3-tert-butyl-5-hydroxymethylbenzoate (2.0 g) was alkylated with ethyl iodide analogously to the conditions of O5.043. 1.18 g of the title compound were obtained.

Sources & evidence

ORD record: ord-94e5a926e78043e1862717a48ec4acb8
Source dataset: uspto-grants-2012_06
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08198272B2

Reaction notes

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