HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Methoxy-6-methylsulfanyl-4-trifluoromethyl-benzoyl chloride → Rac-n-(3-cyclohexyl-1-methyl-piperidin-3-yl)-2-methoxy-6-methylsulfanyl-4-trifluoromethyl-benzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Methoxy-6-methylsulfanyl-4-trifluoromethyl-benzoyl chloride | HCID 59438501 | — |
| Reactant | Rac-3-cyclohexyl-1-methyl-piperidin-3-ylamine | HCID 59438512 | — |
| Product | Rac-n-(3-cyclohexyl-1-methyl-piperidin-3-yl)-2-methoxy-6-methylsulfanyl-4-trifluoromethyl-benzamide | HCID 59438488 | — |
Reaction Steps
In analogy to the procedure described for the synthesis of example 16, the title compound was prepared from rac-3-cyclohexyl-1-methyl-piperidin-3-ylamine (Example A.11) and 2-methoxy-6-methylsulfanyl-4-trifluoromethyl-benzoyl chloride (Example B6). MS (m/e): 445.2 (MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09067911B2 |
| Source dataset | uspto-grants-2015_06 |
| ORD ID | ord-3cfef8b66159419993dcb692614d7260 |
| Source note | uspto-grants-2015_06 |