Methanol → HCID 90409192, compound

HRID 2177626Notes

Reaction equation

HRID 2177626 reaction equation
F[C:2]1[CH:3]=[N:4][C:5]([N:8]2[C:16]3[CH:15]=[CH:14][N:13]=[C:12]([CH3:17])[C:11]=3[N:10]=[CH:9]2)=N[CH:7]=1.[CH3:18]O>[Pd].[Pt].CC(O)=O>[CH3:17][C@H:12]1[C:11]2[N:10]=[CH:9][N:8]([C:5]3[CH:18]=[CH:7][CH:2]=[CH:3][N:4]=3)[C:16]=2[CH2:15][CH2:14][NH:13]1

Participants

6

Reactant 2

HCID 887MethanolHCID 90408675HCID 90408675, compound

Product 1

HCID 90409192HCID 90409192, compound

Reagents, catalysts & solvents 3

HCID 23938PalladiumCatalystHCID 23939PlatinumCatalystHCID 176Acetic AcidSolvent

Procedure

The title compound was prepared in a manner analogous to Example 153, Step D substituting the product from Example 191, Step 2 for 1-(5-fluoropyrimidin-2-yl)-4-methyl-1H-imidazo[4,5-c]pyridine, Pd/C for Pt/C and MeOH for AcOH. MS (ESI) mass calcd. C12H14N4, 214.1. m/z found, 215.1 [M+H]+.

Sources & evidence

ORD record
ord-50d63f61024242d0b40de6216a751f07
Source dataset
uspto-grants-2015_06
Patent number
US09066946B2

Reaction notes

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