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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2177641Generated: October 30, 2026

HCID 90409398, compound → HCID 90409551, compound

https://huagongshe.com/reaction/2177641

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 90409398HCID 90409398—
SolventHydrochloric AcidHCID 313—
Solvent1,4-DioxaneHCID 31275—
ProductHCID 90409551HCID 9040955192.3%

Reaction Conditions

Temperature90 °C

Reaction Steps

The product of Example 238, Step 3 (90 mg, 0.22 mmol) was dissolved in a solution of HCl in dioxane (4M, 2 mL). The reaction was heated at 90° C. for 16 h. The solvent was removed in vacuo to afford the title compound (50 mg, 92%). MS (ESI) mass calcd. C13H15FN4, 246.10; m/z found, 247.16 [M+H]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09066946B2
Source datasetuspto-grants-2015_06
ORD IDord-05d5592fc33c4806adf19ee49ba81df2
Source noteuspto-grants-2015_06