2-Chloro-4-fluorobenzoic acid → 2-Chloro-4-fluorobenzoyl chloride

HRID 2177646Notes

Reaction equation

HRID 2177646 reaction equation
[Cl:1][C:2]1[C:10](C(F)(F)F)=[CH:9][CH:8]=[CH:7][C:3]=1[C:4]([Cl:6])=[O:5].ClC1C=C([F:25])C=CC=1C(O)=O.ClC1C(C(F)(F)F)=CC=CC=1C(O)=O>>[Cl:1][C:2]1[CH:10]=[C:9]([F:25])[CH:8]=[CH:7][C:3]=1[C:4]([Cl:6])=[O:5]

Participants

4

Reactant 3

HCID 752592-Chloro-4-fluorobenzoic acidHCID 27366772-Chloro-3-(trifluoromethyl)benzoic acidHCID 38276332-Chloro-3-(trifluoromethyl)benzoyl chloride

Product 1

HCID 27365462-Chloro-4-fluorobenzoyl chloride

Procedure

The title compound was prepared in a manner analogous to Intermediate 12 substituting 2-chloro-4-fluorobenzoic acid for 2-chloro-3-(trifluoromethyl)benzoic acid.

Sources & evidence

ORD record
ord-288e92698db9495e8b5a9edab077395b
Source dataset
uspto-grants-2015_06
Patent number
US09066946B2

Reaction notes

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