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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2177646Generated: October 30, 2026

2-Chloro-4-fluorobenzoic acid → 2-Chloro-4-fluorobenzoyl chloride

https://huagongshe.com/reaction/2177646

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Chloro-4-fluorobenzoic acidHCID 75259—
Reactant2-Chloro-3-(trifluoromethyl)benzoic acidHCID 2736677—
Reactant2-Chloro-3-(trifluoromethyl)benzoyl chlorideHCID 3827633—
Product2-Chloro-4-fluorobenzoyl chlorideHCID 2736546—

Reaction Steps

The title compound was prepared in a manner analogous to Intermediate 12 substituting 2-chloro-4-fluorobenzoic acid for 2-chloro-3-(trifluoromethyl)benzoic acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09066946B2
Source datasetuspto-grants-2015_06
ORD IDord-288e92698db9495e8b5a9edab077395b
Source noteuspto-grants-2015_06