Phenylboronic Acid → Ethyl 6-(benzenesulphonylmethyl)-2-methoxy-3-phenylbenzoate

HRID 2177713Notes

Reaction equation

HRID 2177713 reaction equation
O1[CH:5]=[CH:4][C:3]([C:6]2[C:7]([O:28][CH3:29])=[C:8]([C:14]([CH2:17][S:18]([C:21]3[CH:26]=[CH:25][CH:24]=[CH:23][C:22]=3C)(=[O:20])=[O:19])=[CH:15][CH:16]=2)[C:9]([O:11][CH2:12][CH3:13])=[O:10])=[CH:2]1.[C:30]1(S(CC2C(C(OCC)=O)=C(OC)C(Br)=CC=2)(=O)=O)C=CC=C[CH:31]=1.C1(B(O)O)C=CC=CC=1>>[C:21]1([S:18]([CH2:17][C:14]2[C:8]([C:9]([O:11][CH2:12][CH3:13])=[O:10])=[C:7]([O:28][CH3:29])[C:6]([C:3]3[CH:2]=[CH:31][CH:30]=[CH:5][CH:4]=3)=[CH:16][CH:15]=2)(=[O:19])=[O:20])[CH:22]=[CH:23][CH:24]=[CH:25][CH:26]=1

Participants

4

Reactant 3

HCID 66827Phenylboronic AcidHCID 67107394Ethyl 6-(benzenesulphonylmethyl)-3-bromo-2-methoxybenzoate2×HCID 67107552Ethyl 3-(furan-3-yl)-2-methoxy-6-(2-methylbenzenesulphonylmethyl)benzoate

Product 1

HCID 67106354Ethyl 6-(benzenesulphonylmethyl)-2-methoxy-3-phenylbenzoate

Procedure

Prepared by proceeding in a similar manner to Intermediate 28, starting from ethyl 6-(benzenesulphonylmethyl)-3-bromo-2-methoxybenzoate (Intermediate 61) and phenylboronic acid.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-a90754eda35f40cab40f938eb5d22f42
Source dataset
uspto-grants-2015_06
Patent number
US09067905B2

Reaction notes

Loading…