HRID2177803

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID11587208

1-(Oxan-2-yl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole

C14H23BN2O3

结构：CCOC(=O)c1c(CS(=O)(=O)c2ccccc2)ccc(-c2ccoc2)c1O

HCID67107629

未命名化合物

结构：CCc1ccc(CS(=O)(=O)c2ccccc2)c(C(=O)OC)c1OS(=O)(=O)C(F)(F)F

HCID86677116

未命名化合物

2 次

PRODUCTS

生成物

结构：CCc1ccc(CS(=O)(=O)c2ccccc2)c(C(=O)OC)c1-c1ccnn1C1CCCCO1

HCID67107802

未命名化合物

PROCEDURE

实验过程

Prepared by proceeding in a similar manner to Intermediate 36, starting from methyl 6-(benzenesulphonylmethyl)-3-ethyl-2-(trifluoromethanesulphonyloxy)benzoate (Intermediate 127) and 1-(2-tetrahydropyranyl)-1H-pyrazole-5-boronic acid pinacol ester as an opaque foam which was used without further characterization.

WORKUP

后处理

customPrepared

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-cc5daac8481843909d9a9c587955de90
来源数据集: uspto-grants-2015_06
DOI: 10.6084/m9.figshare.5104873.v1
专利: US09067905B2
来源说明: uspto-grants-2015_06

反应 SMILES

C1(S(CC2C(C(OCC)=O)=C(O)C(C3C=COC=3)=CC=2)(=O)=O)C=CC=CC=1.[C:28]1([S:34]([CH2:37][C:38]2[C:43]([C:44]([O:46][CH3:47])=[O:45])=[C:42](OS(C(F)(F)F)(=O)=O)[C:41]([CH2:56][CH3:57])=[CH:40][CH:39]=2)(=[O:36])=[O:35])[CH:33]=[CH:32][CH:31]=[CH:30][CH:29]=1.[O:58]1[CH2:63][CH2:62][CH2:61][CH2:60][CH:59]1[N:64]1[C:68](B2OC(C)(C)C(C)(C)O2)=[CH:67][CH:66]=[N:65]1>>[C:28]1([S:34]([CH2:37][C:38]2[C:43]([C:44]([O:46][CH3:47])=[O:45])=[C:42]([C:68]3[N:64]([CH:59]4[CH2:60][CH2:61][CH2:62][CH2:63][O:58]4)[N:65]=[CH:66][CH:67]=3)[C:41]([CH2:56][CH3:57])=[CH:40][CH:39]=2)(=[O:36])=[O:35])[CH:33]=[CH:32][CH:31]=[CH:30][CH:29]=1