Pyrrolidine → HCID 69914985, compound

HRID 2177807Notes

Reaction equation

HRID 2177807 reaction equation
[Br:1][C:2]1[C:3]([O:22][CH3:23])=[C:4]([C:9]([CH2:12][S:13]([N:16]2[CH2:21][CH2:20][CH2:19][CH2:18]C2)(=[O:15])=[O:14])=[CH:10][CH:11]=1)[C:5]([O:7][CH3:8])=[O:6].[Na+].BrC1C=CC(CS([O-])(=O)=O)=C(C(OC)=O)C=1OC.N1CCCC1>>[Br:1][C:2]1[C:3]([O:22][CH3:23])=[C:4]([C:9]([CH2:12][S:13]([N:16]2[CH2:18][CH2:19][CH2:20][CH2:21]2)(=[O:14])=[O:15])=[CH:10][CH:11]=1)[C:5]([O:7][CH3:8])=[O:6]

Participants

4

Reactant 3

HCID 31268PyrrolidineHCID 69915004HCID 69915004, compoundHCID 87271490HCID 87271490, compound2×

Product 1

HCID 69914985HCID 69914985, compound

Procedure

Prepared by proceeding in a similar manner to Intermediate 147, starting from methyl (4-bromo-3-methoxy-2-methoxycarbonylphenyl)-methanesulphonic acid sodium salt (Intermediate 148) and pyrrolidine as a white solid.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-2b624e90b93f4e2194b23eaf4f2da097
Source dataset
uspto-grants-2015_06
Patent number
US09067905B2

Reaction notes

Loading…