Hydrochloric Acid → HCID 58065593, compound

Participants

Reaction Steps

3-Amino-6-(4-{2-[(2-methoxyethyl)amino]ethyl}phenyl)-N-pyridin-3-ylpyrazine-2-carboxamide was prepared using analogous procedures to those described in Example 6, except that 2-methoxyethylamine was used instead of 3-methoxypropylamine in step (v). MeCN was added to 3-Amino-6-(4-{2-[(2-methoxyethyl)amino]ethyl}phenyl)-N-pyridin-3-ylpyrazine-2-carboxamide and 0.5 M-aqueous HCl (20 mL) was also added. The resulting yellow solution was then lyophilized, which afforded the title compound as a tri-hydrochloride salt.

Provenance & Evidence