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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2178129Generated: October 29, 2026

3-Chloro-4-fluorobenzenesulphonyl chloride → 3-chloro-N-(2,4-dimethoxybenzyl)-4-fluoro-N-(5-fluoropyridin-2-yl)benzenesulfonamide

https://huagongshe.com/reaction/2178129

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Chloro-4-fluorobenzenesulphonyl chlorideHCID 145222—
ReactantN-(2,4-dimethoxybenzyl)-5-fluoropyridin-2-amineHCID 58042270—
Product3-chloro-N-(2,4-dimethoxybenzyl)-4-fluoro-N-(5-fluoropyridin-2-yl)benzenesulfonamideHCID 117653299—

Reaction Steps

The title compound was prepared according to the method described for Preparation 18 using N-(2,4-dimethoxybenzyl)-5-fluoropyridin-2-amine (Preparation 20) and 4-fluoro-5-chlorobenzenesulfonyl chloride.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09067922B2
Source datasetuspto-grants-2015_06
ORD IDord-74ce88b37d8c4168994ca27c7b623020
Source noteuspto-grants-2015_06