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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2178135Generated: October 31, 2026

2-Chloro-4-fluorobenzonitrile → 5-Bromo-2-(4-cyano-3-chlorophenoxy)-3-fluorobenzonitrile

https://huagongshe.com/reaction/2178135

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Chloro-4-fluorobenzonitrileHCID 109000—
Reactant5-Bromo-3-fluoro-2-hydroxybenzonitrileHCID 58076937—
Product5-Bromo-2-(4-cyano-3-chlorophenoxy)-3-fluorobenzonitrileHCID 117653206—

Reaction Steps

The title compound was prepared according to the method described for Preparation at 120° C. for 68 hours using 5-bromo-3-fluoro-2-hydroxybenzonitrile (WO 2006022374) and 2-chloro-4-fluorobenzonitrile.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09067922B2
Source datasetuspto-grants-2015_06
ORD IDord-80dae758a1da4423a27d1013731f4feb
Source noteuspto-grants-2015_06