HRID2178153

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID23145481

未命名化合物

结构：C[C@@]1(c2cc(N)ccc2F)C[C@@H](C(F)(F)F)OC(N)=N1

HCID71663148

未命名化合物

PRODUCTS

生成物

结构：C[C@@]1(c2cc(NC(=O)c3ccc(C(F)F)cn3)ccc2F)C[C@@H](C(F)(F)F)OC(N)=N1

HCID71667736

未命名化合物

PROCEDURE

实验过程

The coupling of (4S,6S)-4-(5-amino-2-fluorophenyl)-4-methyl-6-(trifluoromethyl)-5,6-dihydro-4H-1,3-oxazin-2-amine (XI-1) and 5-(difluoromethyl)picolinic acid [J. D. Scott et al. WO2011044181 (2011)] following General Procedure G yielded the title compound as a colorless amorphous solid. MS: m/z=447.5 [M+H]+.