HRID2178161

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID57475856

未命名化合物

反应SMILES：C[C@@]1(c2cc(N)ccc2F)C[C@@H](C(F)(F)F)OC(N)=N1

HCID71663148

未命名化合物

PRODUCTS

产物

反应SMILES：C[C@@]1(c2cc(NC(=O)c3nn(C(F)F)cc3Cl)ccc2F)C[C@@H](C(F)(F)F)OC(N)=N1

HCID71668046

未命名化合物

PROCEDURE

实验过程

The coupling of (4S,6S)-4-(5-amino-2-fluorophenyl)-4-methyl-6-(trifluoromethyl)-5,6-dihydro-4H-1,3-oxazin-2-amine (XI-1) and 4-chloro-1-(difluoromethyl)-1H-pyrazole-3-carboxylic acid [D. Banner et al. WO2011069934 (2011)] following General Procedure F yielded the title compound as an off-white solid. MS: m/z=470.4 [M+H]+.