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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 217822Generated: October 29, 2026

2-Fluoro-5-(trifluoromethyl)phenyl isocyanate → HCID 44134089, compound

https://huagongshe.com/reaction/217822

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Fluoro-5-(trifluoromethyl)phenyl isocyanateHCID 2733380—
ReactantHCID 46901090HCID 46901090—
ProductHCID 44134089HCID 4413408981%

Reaction Steps

Method F2 was used with 2-fluoro-5-trifluoromethyl-phenylisocyanate and 8-(4-amino-3-fluorophenoxy)-2-methylpyrido[2,3-b]pyrazin-3(4H)-one to afford the title compound, yield 81%.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08198279B2
Source datasetuspto-grants-2012_06
ORD IDord-f1ad0b05f68d4f319463b2b7d24d90a8
Source noteuspto-grants-2012_06