HCID 123164601, compound → HCID 89505938, compound

Participants

Reaction Conditions

Reaction Steps

1-[3-(2-Methoxyethenyl)pyridin-2-yl]piperidin-2-one a4-2 (0.340 g, 1.464 mmol, 1 eq) is dissolved in a mixture of formic acid and water (10 ml/0.5 ml). The reaction mixture is heated at 50° C. overnight. The solvent is removed under reduced pressure to afford crude [2-(2-oxopiperidin-1-yl)pyridin-3-yl]acetaldehyde a4-3 which is used in the next step without any further purification.

Provenance & Evidence