HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,3-Dichlorophenol → HCID 17370750, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,3-Dichlorophenol | HCID 11334 | — |
| Reactant | Propanoic acid, 2-bromo-2-methyl-, ethyl ester | HCID 11745 | — |
| Reactant | Potassium Hydroxide | HCID 14797 | — |
| Product | HCID 17370750 | HCID 17370750 | — |
Reaction Steps
Potassium hydroxide-mediated reaction of ethyl 2-bromo-2-methylpropanoate with 2,3-dichlorophenol provided ethyl 2-(2,3-dichlorophenoxy)-2-methylpropanoate. After reduction to the corresponding aldehyde with diisobutylaluminum hydride, reductive amination with 2-aminoethanol provided the requisite 2-aminoethanol derivative.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09067934B2 |
| Source dataset | uspto-grants-2015_06 |
| ORD ID | ord-3459c8a357344738a5d808ecae1e4fd6 |
| Source note | uspto-grants-2015_06 |