Salicylaldehyde oxime → HCID 68379933, compound

HRID 2178715Notes

Reaction equation

HRID 2178715 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([OH:8])=[C:4](I)[CH:3]=1.[F:10][C:11]([F:18])([F:17])[C:12]1[CH:16]=[CH:15][NH:14][N:13]=1.C(=O)([O-])[O-].[Cs+].[Cs+].OC1C=CC=CC=1C=NO>[Cu]=O>[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([OH:8])=[C:4]([N:14]2[CH:15]=[CH:16][C:12]([C:11]([F:18])([F:17])[F:10])=[N:13]2)[CH:3]=1

Participants

6

Reactant 4

HCID 7200Salicylaldehyde oximeHCID 10796Cesium carbonateHCID 6202344-Chloro-2-iodophenolHCID 18070343-(Trifluoromethyl)pyrazole

Product 1

HCID 68379933HCID 68379933, compound

Reagents, catalysts & solvents 1

HCID 14829Copper oxideCatalyst

Procedure

A mixture of 4-chloro-2-iodophenol and 3-(trifluoromethyl)-1H-pyrazole was treated with copper oxide, cesium carbonate and 2-hydroxybenzaldehyde oxime to produce 4-chloro-2-[3-(trifluoromethyl)-1H-pyrazol-1-yl]phenol.

Sources & evidence

ORD record
ord-d949534a2a2745f39347e28c7aee8850
Source dataset
uspto-grants-2015_06
Patent number
US09067934B2

Reaction notes

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