HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-(2-Oxo-3-piperidyl)phthalimide → 2-(2-Methoxy-4,5-dihydro-3H-pyrrol-3-yl)isoindole-1,3-dione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-(2-Oxo-3-piperidyl)phthalimide | HCID 135339 | — |
| Reactant | 2-(2-Oxopyrrolidin-3-yl)isoindoline-1,3-dione | HCID 67265871 | — |
| Product | 2-(2-Methoxy-4,5-dihydro-3H-pyrrol-3-yl)isoindole-1,3-dione | HCID 67265806 | — |
Reaction Steps
By analogy with the method described in example 1 (step 1.1), using 2-(2-Oxo-pyrrolidin-3-yl)-isoindole-1,3-dione (prepared by analogy to the method described in (Heterocycles (1996), 42(2), 537-42, Enantiomer (2001), 6(5), 275-279, Synthesis (1991), (5), 417-20)) in place of 3-phtalimidopiperidin -2-one, the compound was obtained as a white powder.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08198287B2 |
| Source dataset | uspto-grants-2012_06 |
| ORD ID | ord-fc3c78900e164f7cbdf28f70d35e43db |
| Source note | uspto-grants-2012_06 |