HCID 86636837, compound → HCID 69023817, compound

Participants

Reaction Steps

10-azido-10-methyl-2-pyridin-4-yl-7,8,9,10-tetrahydro-6H -pyrimido[1,2-a]azepin-4-one was reduced by using H-Cube™ technology (from THALES Nanotechnology, full H2, Pd/C as catalyst, 1 mL/min and 50° C.). After an acid-basic work-up, (+/−)10-amino-1 0-methyl-2-pyridin-4-yl-7,8,9,10-tetrahydro-6H-pyrimido[1,2-a]azepin-4-one was obtained and the compound was used as such in the next step.

Provenance & Evidence