HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Bromo-2-chlorophenol → O-(2-chloro-4-bromophenyl)hydroxylamine hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Bromo-2-chlorophenol | HCID 19859 | — |
| Reactant | hydroxylamine-O-sulfonic acid | HCID 76284 | — |
| Product | O-(2-chloro-4-bromophenyl)hydroxylamine hydrochloride | HCID 68109187 | 39.8% |
Reaction Steps
4-bromo-2-chlorophenol (110 g, 0.53 mol) was reacted with hydroxylamine-O-sulfonic acid (15 g, 0.13 mol) using the procedure of Example 29, step A to give O-(2-chloro-4-bromophenyl)hydroxylamine hydrochloride (13.4 g, 28%) as a light brown solid: 1H NMR (DMSO, 400 MHz) δ 7.61 (d, J=2.0 Hz, 1H), 7.48 (d, J=2.4 Hz, 1H), 7.47 (s, 1H), 5.81 (br s, 3H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09067949B2 |
| Source dataset | uspto-grants-2015_06 |
| ORD ID | ord-7de2cf3a44434301a2e2b76f2fd10413 |
| Source note | uspto-grants-2015_06 |