反应详情

4-bromo-2-chlorophenol (110 g, 0.53 mol) was reacted with hydroxylamine-O-sulfonic acid (15 g, 0.13 mol) using the procedure of Example 29, step A to give O-(2-chloro-4-bromophenyl)hydroxylamine hydrochloride (13.4 g, 28%) as a light brown solid: 1H NMR (DMSO, 400 MHz) δ 7.61 (d, J=2.0 Hz, 1H), 7.48 (d, J=2.4 Hz, 1H), 7.47 (s, 1H), 5.81 (br s, 3H).