Hydrochloric Acid → HCID 68108585, compound

Participants

Reaction Steps

The product of step E was converted to the HCl salt using the procedure of Example 32, step C providing 7-(phenylsulfonyl)-1,2,3,4-tetrahydrobenzofuro[3,2-c]pyridine hydrochloride (22 mg, 94%, AUC HPLC 97.4%) as a white solid: mp 235-238° C.: 1H NMR (DMSO-d6, 300 MHz) δ 9.69 (br s, 2H), 8.27 (s, 1H), 7.98 (d, J=6.9 Hz, 2H), 7.89-7.81 (m, 2H), 7.70-7.56 (m, 3H), 4.33 (s, 2H), 3.53 (t, J=6.0 Hz, 2H), 3.16-3.14 (m, 2H); ESI MS m/z 314 [M+H]+.

Provenance & Evidence