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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2179551Generated: November 2, 2026

(3-Aminopropyl)triethoxysilane → 2-(6-Hydroxy-3-oxo-3H-xanthen-9-yl)benzoic acid

https://huagongshe.com/reaction/2179551

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(3-Aminopropyl)triethoxysilaneHCID 13521—
ReactantFluorescein 5-isothiocyanateHCID 18730—
Solvent(+-)-2-ButanolHCID 6568—
Product2-(6-Hydroxy-3-oxo-3H-xanthen-9-yl)benzoic acidHCID 3383—
ProductSilaneHCID 23953—

Reaction Steps

50 μl APS (γ-amino propyltriethoxyl silane) and 1 ml FITC (fluorescein isothiocyanate, 1 mg/ml ethanol solution) are added into a 4 ml absolute ethyl ethanol under obturation condition to react for 12 hours, so as to obtain a precursor solution upon coupling of fluoresceine and silane coupling agent. The method for preparing the precursor solution is common knowledge in prior art. 3.65 ml ethanol/water mixture (ratio of ethanol to water is 8), 1.2 ml ethanol and 100

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09068084B2
Source datasetuspto-grants-2015_06
ORD IDord-b356f3e9bd554eda81e0356cf5b4ce32
Source noteuspto-grants-2015_06