HCID 86650119, compound → HCID 58111116, compound

Participants

Reaction Steps

To a stirred solution of benzyl (1S,3R)-3-(4-ethylpiperazine-1-carbonyl)-2,2-dimethylcyclobutylcarbamate (above step 1, 780 mg) in EtOAc (20 ml) 10% Pd/C (catalytic amount) was added at room temperature and the reaction mixture was stirred under H2 gas atmosphere for 12 hours. After completion of the reaction (monitored by TLC), the reaction mixture was filtered through a celite bed and the obtained filtrate concentrated under reduced pressure to afford the title compound as a liquid which was proceeded as such for next reaction without characterization. Yield has been calculated as 100%.

Provenance & Evidence