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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2179961Generated: October 26, 2026

4-Chloro-2,5-difluorobenzonitrile → (3-(5-Chloro-2-cyano-4-fluorophenoxy)-3-(6-methoxy-2-pyridinyl)-propyl]-carbamic acid 1,1-dimethylethyl ester

https://huagongshe.com/reaction/2179961

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Chloro-2,5-difluorobenzonitrileHCID 11275302—
Reactant[3-Hydroxy-3-(6-methoxy-2-pyridinyl)propyl]carbamic acid 1,1-dimethylethyl esterHCID 69798380—
Product(3-(5-Chloro-2-cyano-4-fluorophenoxy)-3-(6-methoxy-2-pyridinyl)-propyl]-carbamic acid 1,1-dimethylethyl esterHCID 86759697—

Reaction Steps

The sub-title compound was prepared by the method of Example 58 (c) using [3-hydroxy-3-(6-methoxy-2-pyridinyl)propyl]carbamic acid 1,1-dimethylethyl ester (Example 61 (b)) and 4-chloro-2,5-difluorobenzonitrile.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06887871B2
Source datasetuspto-grants-2005_05
ORD IDord-de17b066fe074c6f96274055290c3e24
Source noteuspto-grants-2005_05