HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dichloromethane → 3-Chloro-1-(3-thienyl)-1-propanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dichloromethane | HCID 6344 | — |
| Reactant | 1-(3-Thienyl)-2-propen-1-one | HCID 22489927 | — |
| Solvent | Hydrochloric Acid | HCID 313 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | 3-Chloro-1-(3-thienyl)-1-propanone | HCID 22489902 | 91% |
Reaction Steps
The product from step (b) (1.288 g, 9.3 mmol) was dissolved in a mixture of diethyl ether (30 ml) and dichloromethane (20 ml) and 1M hydrochloric acid in diethyl ether (25 ml) added. The reaction was stirred for 18 h at room temperature. The solvent was removed in vacuo to give the title compound (1.482 g, 91%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06887871B2 |
| Source dataset | uspto-grants-2005_05 |
| ORD ID | ord-5a3f24bade6d41e8a5539e8cdf4d5aaa |
| Source note | uspto-grants-2005_05 |