HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Pyridinemethanol → HCID 22490028, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Pyridinemethanol | HCID 7510 | — |
| Reactant | 4-(4-Fluoro-2-methylindol-5-yloxy)-7-hydroxy-6-methoxycinnoline | HCID 135749776 | — |
| Product | HCID 22490028 | HCID 22490028 | 32% |
Reaction Steps
Using an analogous procedure to that described in Example 20, 4-(4-fluoro-2-methylindol-5-yloxy)-7-hydroxy-6-methoxycinnoline (0.2 g, 0.5 mol), (prepared as described in Example 4), was reacted with 3-(hydroxymethyl)pyridine (60 μl, 0.9 mmol) to give 4-(4-fluoro-2-methylindol-5-yloxy)-6-methoxy-7-(3-pyridylmethoxy)cinnoline (80 mg, 32%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06887874B2 |
| Source dataset | uspto-grants-2005_05 |
| ORD ID | ord-2d17094f9e7d4861b49acda94be8a1a6 |
| Source note | uspto-grants-2005_05 |