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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 21802Generated: October 28, 2026

1-Methylpiperazine → 2-(N-methylpiperazinyl)ethylphthalimide

https://huagongshe.com/reaction/21802

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-MethylpiperazineHCID 53167—
Reactant2-BromoethylphthalimideHCID 21960021—
SolventDiethyl EtherHCID 3283—
Product2-(N-methylpiperazinyl)ethylphthalimideHCID 54446072—

Reaction Steps

2-Bromoethylphthalimide (508 mg; 2.0 mmoles) and N-methylpiperazine (0.44 ml; 4.0 mmoles) were dissolved in anhydrous ethyl ether (5 ml). Reaction times and process as per Example 1.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05424451
Source datasetuspto-grants-1995_06
ORD IDord-4521b61fb1534bbd9013fa2f9ed61a3f
Source noteuspto-grants-1995_06