反应详情

A solution of Example 106A (0.33 g, 0.82 mmol), and 10% palladium on charcoal (0.13 g) in THF (8 mL) at room temperature was stirred for 16 hours under an atmosphere of hydrogen gas, filtered, and concentrated. The concentrate was dissolved in saturated HCl/dioxane (5 mL), stirred for 1 hour, concentrated, treated with diethyl ether, then concentrated to provide the desired product.

1. filtrationfiltered
2. concentrationconcentrated
3. dissolutionThe concentrate was dissolved in saturated HCl/dioxane (5 mL)
4. concentrationconcentrated
5. additiontreated with diethyl ether
6. concentrationconcentrated