HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Cyanide → Methyl 3-(cyanomethyl)benzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Cyanide | HCID 9032 | — |
| Reactant | Methyl 3-(bromomethyl)benzoate | HCID 517981 | — |
| Solvent | Dimethyl Sulfoxide | HCID 679 | — |
| Product | Methyl 3-(cyanomethyl)benzoate | HCID 10821136 | — |
Reaction Steps
A solution of methyl 3-(bromomethyl)benzoate (2.29 g, 0.01 mol) and potassium cyanide (3.26 g, 0.05 mol) in DMSO (20 mL) was heated to 100° C. for 1 h. The reaction mixture was cooled, partitioned between ether and water, washed with brine, dried (Na2SO4) and concentrated to give the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06887863B2 |
| Source dataset | uspto-grants-2005_05 |
| ORD ID | ord-0002a93fec8f4387b3c67b376ff03867 |
| Source note | uspto-grants-2005_05 |