Stannane, tributyl(1-ethoxyethenyl)- → 1-(7-Ethoxy-4-ethyl-2,2-dimethyl-2H-chromen-6-yl)-ethanone

HRID 2180482Notes

Reaction equation

HRID 2180482 reaction equation
Br[C:2]1[CH:3]=[C:4]2[C:9](=[CH:10][C:11]=1[O:12][CH2:13][CH3:14])[O:8][C:7]([CH3:16])([CH3:15])[CH:6]=[C:5]2[CH2:17][CH3:18].C([Sn](CCCC)(CCCC)[C:24]([O:26]CC)=[CH2:25])CCC>C1COCC1>[CH2:13]([O:12][C:11]1[CH:10]=[C:9]2[C:4]([C:5]([CH2:17][CH3:18])=[CH:6][C:7]([CH3:16])([CH3:15])[O:8]2)=[CH:3][C:2]=1[C:24](=[O:26])[CH3:25])[CH3:14]

Participants

4

Reactant 2

HCID 619414Stannane, tributyl(1-ethoxyethenyl)-HCID 224909746-Bromo-4-ethyl-7-ethoxy-2,2-dimethyl-2H-chromene2×

Product 1

HCID 224908291-(7-Ethoxy-4-ethyl-2,2-dimethyl-2H-chromen-6-yl)-ethanone

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

Following General Procedure H, a solution of 6-bromo-4-ethyl-7-ethoxy-2,2-dimethyl-2H-chromene (Compound 16, 595 mg, 2.08 mmol) in THF was treated with tributyl(1-ethoxyvinyl)tin (1.50 g, 4.17 mmol) to give the title compound as a yellow solid.

Sources & evidence

ORD record
ord-08c6a5555c1e437387e4fe1e523668fc
Source dataset
uspto-grants-2005_05
Patent number
US06887896B1

Reaction notes

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