1-Iodopropane → 1-(4-Isopropyl-2,2-dimethyl-7-propoxy-2H-chromen-6-yl)-ethanone

HRID 2180486Notes

Reaction equation

HRID 2180486 reaction equation
[OH:1][C:2]1[CH:11]=[C:10]2[C:5]([C:6]([CH:14]([CH3:16])[CH3:15])=[CH:7][C:8]([CH3:13])([CH3:12])[O:9]2)=[CH:4][C:3]=1[C:17](=[O:19])[CH3:18].I[CH2:21][CH2:22][CH3:23]>>[CH:14]([C:6]1[C:5]2[C:10](=[CH:11][C:2]([O:1][CH2:21][CH2:22][CH3:23])=[C:3]([C:17](=[O:19])[CH3:18])[CH:4]=2)[O:9][C:8]([CH3:13])([CH3:12])[CH:7]=1)([CH3:15])[CH3:16]

Participants

3

Reactant 2

HCID 336431-IodopropaneHCID 224909177-Hydroxy-4-isopropyl-2,2-dimethyl-2H-chromen-6-yl-ethanone2×

Product 1

HCID 224907711-(4-Isopropyl-2,2-dimethyl-7-propoxy-2H-chromen-6-yl)-ethanone

Procedure

Following General Procedure A, 1-(7-hydroxy-4-isopropyl-2,2-dimethyl-2H-chromen-6-yl)ethanone (Compound 62, 400 mg, 1.38 mmol) and 1-iodopropane (0.70 mL, 6.90 mmol) were reacted to produce the title compound as a colorless oil.

Workup

  1. customwere reacted

Sources & evidence

ORD record
ord-3aa177f4ac48465ea84f9747143f7d65
Source dataset
uspto-grants-2005_05
Patent number
US06887896B1

Reaction notes

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